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puberty blockers

Aug 31 2026

NIH Study: Drugs, Hormones Don’t Help Sexually Confused Youth

The National Institutes of Health funded a multimillion-dollar study where sexually confused children were given puberty blockers and opposite-sex hormones: The experiment showed no improvement in their mental health. 

That’s right, taxpayers financed a Mengele-esque experiment, where children as young as eight were injected with powerful puberty blockers and opposite-sex hormones in order to find out if these “transgender” medical interventions improved their mental health. 

Participants received gift cards for allowing health care workers to damage their bodies. 

The study was first approved under the Obama administration in 2015.

The Heritage Foundation’s Oversight Project released the final report to The Daily Signal, which described the study: 

The National Institutes of Health first allocated a nine-year grant of up to $10 million for the study through the Children’s Hospital of Los Angeles. The study was led by Dr. Johanna Olson-Kennedy, who specializes in “gender-affirming care.”

“Gender-affirming care” is a euphemism for social and physical interventions for mentally confused children who reject their God-given bodies and attempt to live as the opposite sex. 

As the Signal reported: 

The study included people as young as 8 years old. The sample receiving puberty blockers included participants up to age 16, while the sample receiving hormone treatments included participants up to age 20.

The results? 

Well, first of all, as reported by The New York Times two years ago, Dr. Olson-Kennedy initially would not even publish the results “because of politics.” In actuality, she already knew the results showed no mental health benefits: 

The leader of the long-running study said that the drugs did not improve mental health in children with gender distress and that the finding might be weaponized by opponents of the care.

Two years later, “Mental and Emotional Health of Youth after 24 months of Gender-Affirming Medical Care Initiated with Pubertal Suppression” was finally published online at medRxiv(med-archive). The study states: 

[T]he mental health of youth as reported by both themselves and their parents/guardians is relatively stable from baseline over 24 months after starting medical intervention with GnRHa [a puberty suppressant].

So the children’s mental health remained the same: There was no benefit from puberty suppression and opposite-sex hormones.

Dr. Olson-Kennedy has long been an activist for transgenderism. As previously reported by the Daily Citizen, she is “married” to Aydin Olson-Kennedy, a woman who attempts to live as a man. She is a licensed clinical social worker who works as a therapist and as a lecturer and consultant “on topics centered around the social and clinical needs of transgender individuals and their families.” 

Dr. Olson-Kennedy also produced a study on the mutilation of young girls, “Chest Reconstruction and Chest Dysphoria in Transmasculine Minors and Young Adults,” which examined a group of 68 gender confused teens and young women – between the ages of 13 and 24 who had their breasts removed within the past five years.

The girls were given a 10-minute survey about “chest dysphoria,” and the results compared with a non-surgical, gender-dysphoric group. 

Dr. Olson-Kennedy, former Medical Director of The Center for Transyouth Health and Development at Children’s Hospital in Los Angeles, gained notoriety when a video of her surfaced teaching that adolescents make big decisions all the time, so breast removal is no big deal: 

And here’s the other thing about chest surgery. If you want breasts at a later point in your life, you can go and get them.

She is now on staff at Prosilio Care’s Gender Confirmation Center, in Pasadena, California. 

The Signal published a second story about the study, reporting: 

A long-suppressed, taxpayer-funded report on transgender youth found that treatments with puberty blockers and hormones could have lasting negative impacts on bone density and heart health, among other health issues.

In May 2025, the U.S. Department of Health and Human Services (HHS) released an important evaluation of the evidence for how best to treat children and adolescents with “gender dysphoria.” The report listed other damages to children receiving this “care”: 

The “gender-affirming” model of care includes irreversible endocrine and surgical interventions on minors with no physical pathology.

These interventions carry risk of significant harms including infertility/sterility, sexual dysfunction, impaired bone density accrual, adverse cognitive impacts, cardiovascular disease and metabolic disorders, psychiatric disorders, surgical complications, and regret. 

Thankfully, HHS and the Department of Justice are working to shut down the mutilation of children through these unscientific procedures. We look forward to the day when all health care providers view “gender-affirming care” with the same horror that we view lobotomies and bloodletting with leeches. 

Related articles and resources: 

American Society of Plastic Surgeons Backs Away From Supporting ‘Transgender’ Surgeries

Expert in ‘Transitioning’ Children Admits ‘We Were Wrong’ About Puberty Blockers

Focus on the Family Counseling Consultation and Referrals

Helping Children with Gender Identity Confusion

Hospitals and Doctors “Transition” Hundreds of Children with Drugs, Hormones and Surgery

INVESTIGATION: Taxpayers Fund Transgender Experiments on Children

New Video Equips Parents and Counselors to Help ‘Gender Dysphoric’ Children

Questioning Drugs, Hormones and Surgery for Youth Confused about Their Sexual Identity

Transgender Resources

Transgenderism and Minors: What Does the Research Really Show?

U.K.’s Review of Child Gender Policy Reveals Profound Failures That U.S. Still Defends

The WPATH Files Exposes ‘Surgical and Hormonal Experiments on Children’

The WPATH Files – Transgender Interventions Are ‘Unethical Medical Experiments’

Written by Jeff Johnston · Categorized: Sexuality · Tagged: hormones, puberty blockers, transgender

Jan 13 2026

UK Petition to Halt Drug Trial Testing Puberty Blockers on Kids Passes 100,000 Signatures

A UK petition to cancel a clinical trial testing puberty blockers on children surpassed 100,000 signatures yesterday — a critical milestone which qualifies the petition for debate in parliament.

The Pathways Trial, which UK health authorities licensed, approved and agreed to fund in November, plans to test puberty blocking drugs on 226 transgender-identified children between 10 and 15 years old. The experiment will compare the bodies and brains of these children with those of children who don’t receive puberty blockers.

Therapist James Esses created the UK Government and Parliament petition to cancel the Pathways Trial on January 8, citing the known damage puberty blockers cause healthy children.

The UK’s National Health Service (NHS) banned doctors from administering puberty blockers to children outside of clinical trials in 2024 after The Cass Review, an evidentiary review of sex-rejecting medical interventions for minors, found insufficient evidence showing puberty blockers improve the wellbeing of children with sexual identity confusion.

“The government is aware of the potential irreversible impact (physical and emotional) of puberty blockers…,” the petition emphasizes. “Yet, hundreds of thousands of children are about to be given puberty blockers under a government-sanctioned trial.”

Petitions must receive more than 100,000 signatures in six months for parliament to consider debating them. The petition to stop the Pathways Trial reached 100,000 signatures in four days.

“From the bottom of my heart, thank you to each and every one of you who signed my petition to safeguard vulnerable children,” Esses wrote on X.

“Next stop: parliament.”

The petition is part of a “multi-prong” effort to protect children from the Pathways Trial. In December, Esses and detransitioner Keira Bell sent a letter to the regulatory agencies responsible for approving the trial, arguing it fails to uphold the UK’s legal standard for experimenting on humans.

The letter initiated a judicial review of the Pathways Trial which, if successful, will allow a judge to determine whether the UK government erred in approving the experiment.

Esses and Bell argue the Pathways Trial violates at least three ethical requirements for clinical trials.

Ethical clinical trials prioritize the health and safety of their subjects over scientific inquiry. All available evidence shows puberty blockers permanently stunt children’s sexual development, causing reduced reproductive function, infertility and inability to breast feed in women.

New studies further link puberty blockers to problems with cognitive development, compromised bone health and cancer. Children who take puberty blockers generally go on to take wrong-sex hormones, which increases their chances of developing life-altering complications and disease.

Ethical clinical trials study drugs which are more likely to improve patients’ lives than harm them. But puberty blockers offer little — if any — benefit to children with sexual identity confusion.

Further, Esses and Bell argue the Pathways Trial contains significant design flaws which would compromise any positive results.

Most glaringly, the trial does not limit confounding variables. Every child will receive talk therapy and other social support in addition to puberty blockers, making it impossible to determine which intervention correlates with which outcomes.

Ethical clinical trials require subjects’ informed consent. No child can consent to permanent body modifications. Transgender-identified children, which suffer from higher rates of autism spectrum disorder, ADHD, anxiety, depression, eating disorders, suicidality, self-harm and adverse childhood experiences, are arguably even less likely to understand the lasting implications of sex-rejecting procedures.

The letter also questions whether parents can give informed consent for their children to enter Pathways Trial after years of hearing scientists call puberty blockers “safe” and “evidence-based.”

“The expectations of children [seeking to enter the trial] and their parents have been significantly shaped by poorly evidenced narratives regarding the benefits of puberty blockers,” the letter argues.

The letter encapsulates Essen and Bell’s position using a passage from the U.S. Department of Health and Human Services’ comprehensive report on sex-rejecting medical interventions for minors:

It is not ethical to subject adolescents to hormonal and surgical interventions used in [sex-rejecting procedures], even in a research trial, until and unless the state of the evidence suggests a favorable risk/benefit profile for the studied intervention, and the researchers have a well-grounded confidence that the foreseeable risks and burdens have been adequately assessed and can be satisfactorily managed.

Evidence on puberty blockers suggests the drugs harm children with sexual identity confusion far more than they help. Each new piece of research seems to connect the drugs to new, serious complications. Injecting these chemicals into vulnerable children is textbook unethical human experimentation.

Happily, tens of thousands of UK residents understand the ethical dilemmas with Pathways Trial — and will speak up to stop the experiment.

Additional Articles and Resources

England’s NHS Stops Dispensing Puberty Blockers for Children — Not Safe or Effective

U.K.’s Review of Child Gender Policy Reveals Profound Failures That U.S. Still Defends

HHS Finalizes Report Finding Sex-Rejecting Procedures Harm Minors

HHS Releases Report on Harms of ‘Transgender’ Medical Interventions for Minors

New Paper Details ‘Emerging and Accumulating’ Adverse Effects of ‘Gender Affirming’ Estrogen

FTC Begins Investigating ‘Gender-Affirming’ Medical Community for Deception, False Advertising

Written by Emily Washburn · Categorized: Culture · Tagged: puberty blockers, UK

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